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Any Principal Investigator (PI) working or proposing to work with recombinant DNA, human cells, pathogenic microorganisms, primate body fluids, certain animals, or biological toxins must seek approval by the FSU Biological Safety Committee (BSC or IBC). Included in this requirement is research undertaken by FSU appointees in facilities controlled by the University or supported by grants processed through the University. All proposals, regardless of funding source, are subject to review.

In conjunction with the Biological Safety Officer (BSO), the BSC will determine if the research falls within the "NIH Guidelines for Research Involving recombinant DNA".  The BSO will also review the research proposal and determine the appropriate level of biohazard containment.

Generally, the BSO and the Chairperson for the BSC receive research proposals from the grant processing office for the University, such as the Office for Sponsored Research or the Research Foundation. The BSO and the Chairperson for the BSC will initially review and approve the research. If they determine that the proposed research falls within the "NIH Guidelines for Research Involving recombinant DNA" or if they determine that the research involves biological hazards, the BSO will request the BSC members convene for a full committee review of the research proposal.

Once the review is complete, the BSO will confirm that the facilities and safety equipment, including biological safety cabinets, are functioning properly and provide the required training for the PI, faculty, students, and staff conducting the research.

The PI will receive a memorandum from the BSO indicating whether the research is approved by the BSC and stating the minimum level of containment necessary for the research. The research will not be approved if the appropriate safety equipment is not in place. The grant processing office at FSU will receive a copy of the memorandum as well.

Biological Safety will routinely inspect the research facility to ensure that safety equipment; including biological safety cabinets and other safety equipment are functioning properly, and provide refresher training to the PI, faculty, students, and staff. Any deficiency will be reported to the BSC.


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